Dear Editorial Office, Thank you for the opportunity to respond to the editorial on our study of composite electrocardiography and heart-rate-variability indices during percutaneous coronary intervention. We would like to record our appreciation of how the manuscript was handled. The exchange itself — an editorial commentary followed promptly by an authors' reply in the same journal — is exactly the kind of post-publication dialogue that improves a research programme rather than merely defending it, and we are grateful that World Journal of Cardiology makes room for it. The process was both quick and substantive: 79 days from submission to acceptance, with a clear editorial timeline at every stage and an external review that engaged with the scientific content rather than with formalities. The reviewer's comments were specific and constructive, and they helped us sharpen the distinction between the validated construction of the indices and the exploratory clustering that still requires independent validation. Communication from the editorial office was prompt and unambiguous throughout, and the open-access format ensures that the discussion reaches the readers it concerns. We thank the editors, the peer reviewer and the editorial staff for their work, and we look forward to submitting the prospective, reference-standard-anchored study outlined in this reply to your journal. Yours sincerely, Oleksandr P Romanchuk, on behalf of all authors